Mouse Secondary Antibodies
Cayman Chemical GnoderIc AcId A 50mg
A triterpene with diverse biological activities; reduces cell viability, expression SOD1, SOD2, and SOD3, and production of ROS in PC3 prostate cancer cells; inhibits LPS-induced activation of NF-κB, release of TNF-α, IL-1β, and IL-6, and mitochondrial activity in primary mouse cortical microglia; reduces lung MPO activity, neutrophil infiltration, and NF-κB signaling, as well as BALF levels of TNF-α, IL-1β, and IL-6 in a mouse model of LPS-induced lung injury at 20 and 40 mg/kg; reduces weight gain and hepatic lipid accumulation and improves insulin sensitivity in a mouse model of high-fat diet-induced obesity
Biotium Beta-2-Microglobulin (B2M)(246-E9.E7), CF488A conjugate, 0.1mg/mL
Beta-2 microglobulin is a component of the class I major histocompatibility complex (MHC I) where it functions in antigen processing and presentation. Involved in the presentation of peptide antigens to the immune system. Human Beta-2 microglobulin is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human Beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of Beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection. Clone 246 E9.E7 is the same as HLA.ABC.m2.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and
Human IGHG1 MAb 20ug (Sino Biological)
This product is a recombinant monoclonal antibody expressed from HEK293 cells. Then conjugated with horseradish-peroxidase (HRP).
Cayman Chemical LevIstolIde A 10mg
A phthalide with diverse biological activities; inhibits TPA and A23187-induced histamine release from HMC-1 cells at 10 µM; induces the production of ROS, ER stress, and apoptosis in HCT116 cells at 100 µM; prevents ethanol-induced gastric ulcers in rats at 10 mg/kg; decreases aggregation of amyloid-β in brain and improves spatial and learning memory in the APP/PS1 transgenic mouse model of Alzheimer's disease at 2 mg/kg
Sino Biological Mouse Anti-Human IgG Secondary Antibody, Mouse MAb
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, reconbinant human IgG.This antibody was purified by Protein A affinity chromatography.
Cayman Chemical a-MngostIn 100mg
A xanthone with diverse biological activities; inhibits fatty acid synthase and HIV-1 protease (IC50s = 5.54 and 5.12 μM, respectively); active against methicillin-sensitive and -resistant S. aureus strains (MICs = 1.57-12.5 μg/ml); inhibits nitric oxide and PGE2 production in LPS-stimulated RAW 264.7 cells (IC50s = 12.4 and 11.08 μM, respectively); a STING agonist that binds to the C-terminal domain of STING (H232 variant) (Kd = 137 μM); induces expression of an IFN-β-luciferase reporter in HEK293T cells transfected with human STING (H232 variant) at 25 μM; prevents carrageenan-induced paw edema in mice at 20 mg/kg; decreases the viability of LNCaP, 22Rv1, DU145, and PC3 prostate cancer cells in vitro (IC50s = 5.9, 6.9, 22.5, and 12.7 μM, respectively); reduces tumor growth in a 22Rv1 mouse xenograft model at 100 mg/kg
Cayman Chemical Mouse PRoxISME ProlIfRatr
mPPARα Reporter Cells are prepared using INDIGO’s proprietary CryoMite™ process. This cryo-preservation method yields high cell viability post-thaw, and provides the convenience of immediately dispensing healthy, division-competent reporter cells into assay plates. There is no need for intermediate spin-and-wash steps, viability determinations, or cell titer adjustments. [INDIGO Catalog Nos. M00111-32, M00111]
Bio X Cell InVivoMAb Anti-Mouse IL-1 R (CD121a), 100 MG
The InVivoMAb anti-mouse IL-1 R (CD121a) antibody is a monoclonal antibody that reacts with mouse IL-1 receptor type 1. This 80 kDa transmembrane glycoprotein is expressed on various cell types and mediates IL-1 biological responses upon ligand binding.
- Reacts with mouse IL-1 receptor type 1 (CD121a)
- Monoclonal antibody targeting IL-1 receptor
- Transmembrane glycoprotein, 80 kDa
- Binds IL-1α and IL-1β
- Mediates all known IL-1 biological responses
- Purified from cell culture supernatant in an animal-free facility
- Purity ≥95% (SDS-PAGE)
- Endotoxin ≤1EU/mg (LAL assay)
- Sterility: 0.2 μm filtration
- Storage at 4°C, do not freeze
Genscript Corporation CA72-4 Antibody D31 mAb Mo
CA72-4 (Cancer antigen 72-4) also known as Tumor associated glycoprotein (TAG) 72 is a mucin-like protein of high molecular weight (200- 400 kD) CA 72-4 has high specificity for diagnosis of benign diseases It is also a helpful marker in the diagnosis of gastric cancer ovarian carcinoma and colorectal carcinoma
Biolegend PE anti-mouse TCR V 7 [F2 67] Isotype Mouse IgG2a Reactivity Mouse Apps FC Size 100 ug
PE anti-mouse TCR V 7 [F2 67] Isotype Mouse IgG2a Reactivity Mouse Apps FC Size 100 ug
Biotium CD54 / ICAM-1(F4-31C2), CF568 conjugate, 0.1mg/mL
Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.
Biolegend Spark PLUS YG581 anti-mouse/human CD11b [M1/70] Isotype Rat IgG2b Reactivity Mouse Human Cynomolgus Rhesus Apps FC Size 25 ug
Spark PLUS YG581 anti-mouse/human CD11b [M1/70] Isotype Rat IgG2b Reactivity Mouse Human Cynomolgus Rhesus Apps FC Size 25 ug
Cayman Chemical Gngerenon A 10mg
A diarylheptanoid and polyphenol with diverse biological activities; inhibits tyrosinase (IC50 = 9.4 µM for the mushroom enzyme); scavenges DPPH radicals in a cell-free assay (IC50 = 12.6 µM); inhibits JAK2 and p70S6K1 at 5 and 10 µM; selectively decreases the viability of ionizing radiation-induced senescent WI38 fibroblasts over proliferating fibroblasts at 20 µM; prevents increases in body weight but does not affect caloric intake in a mouse model of high-fat diet-induced obesity at 50 mg/kg; decreases tumor weight in an HCT116 colon cancer mouse xenograft model at 5 and 20 mg/kg